Gene Hackman, the legendary Oscar-winning actor, and his wife Betsy Arakawa passed away under tragic circumstances, with their causes of death officially confirmed by authorities. The Santa Fe County Medical Examiner’s Office revealed that Hackman died from hypertensive atherosclerotic cardiovascular disease, with Alzheimer’s disease listed as a significant contributing factor. Arakawa’s death was attributed to hantavirus pulmonary syndrome, a rare but severe respiratory illness transmitted by rodents.
Key Details from the Investigation
- Hackman’s Passing: The 95-year-old actor died on February 18, 2025, at his New Mexico home. His condition, hypertensive atherosclerotic cardiovascular disease, involves hardened arteries due to high blood pressure, a condition linked to heart attacks and strokes. Alzheimer’s disease, which Hackman had battled, likely exacerbated his health decline.
- Arakawa’s Tragic End: Arakawa, 64, died on February 11, 2025. Hantavirus pulmonary syndrome, her confirmed cause of death, is a life-threatening illness spread through rodent droppings or urine. The Centers for Disease Control and Prevention (CDC) notes that early symptoms include fever and muscle aches, progressing rapidly to severe respiratory distress. Read the CDC’s guidelines on hantavirus prevention here.
Initial Speculations and Investigation

The Santa Fe County Sheriff’s Office initially reported no signs of foul play but noted “suspicious” circumstances, including unsecured doors, scattered medication, and the positioning of their bodies. Hackman’s family had speculated carbon monoxide poisoning, though investigators found no evidence of a gas leak.
Family’s Statement
Hackman’s daughters, Elizabeth and Leslie, and granddaughter Annie expressed profound grief, stating: “He was loved and admired by millions … but to us he was always just Dad and Grandpa.”
The couple’s deaths mark the end of an era for Hollywood and their loved ones. As authorities continue to piece together the final moments, the medical examiner’s report underscores the importance of understanding health risks like cardiovascular disease and hantavirus.
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